|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
31. Indole-3-Carbinol extractul fitofarmaceutic moduleaza estrogenul, inhiba proliferarea, cu preventie la cancerul mamar32
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Indole-3-Carbinol prelungeste viata (Lifespan is prolonged with Indole-3-Carbinol) 
| Dieta anti-estrogenica, dieta mediteraneana cu retete culinare: peste marinat, salata de varza alba sau rosie, se taie subtire, se sareaza usor, se stoarce zeama, apoi varza se asaza in salatiera, putin ulei de masline | ||
|
 |
 |
Dieta
mediteraneana creste longevitatea
Dieta mediteraneana creste longevitatea, studiile arata ca populatiile din tarile mediteraneene sint longevivi
40. Dieta mediteraneana traditionala reduce estrogenul endogen la femei sanatoase in postmenopauza
41. Acizii grasi esentiali polinesaturati Omega 3 din Ulei de Peste atenueaza cresterea cancerului mamar, prin activarea neutrala de mediere a sfingomielinaza
Pestele cu ulei de peste contine acizi grasi esentiali Omega 3 iar uleiul de masline contine acizi grasi mononesaturat Omega 9
Scurt si cuprinzator: acizii grasi esentiali sint substante nutritive sanatoase pentru organism ca: Acizii grasi polinesaturati Omega-3, Omega-6, Omega-9,
despre Ulei de peste Omega-3! |
42. Resveratrol un citostatic cu proprietati anti-estrogenice la adenocarcinomul endometrial
43. Resveratrol un produs natural din struguri cu activitate anti-estrogenica, inhiba cancerul mamar
44. Resveratrol cu proprietati de anti-estrogen la cancerul mamar pe linia celulara MCF-7
45. Resveratrol cu proprietati de anti-estrogen la tumora mamara
46. Resveratrol un fitoestrogen cu efect la aromataza 17 beta-hidroxisteroid dehidrogenaza activitate si la cancerul mamar
47. Resveratrol un polifenol din struguri este un agonist pentru receptorul de estrogen
48. Resveratrol este un mixt de agonist/antaginist pentru receptorul alfa si beta al estrogenului
49. Resveratrol cu actiune de preventie la cancer este convertit intrun agent anticancer al metabolitului sau Resveratrol - Piceatanol de citocromul 450 al enzimei CYO1B1 cu specific de estradiol hidroxilaza
50. Indole-3-Carbinol un citostatic natural in tratamentul de cancer mamar
51
Indole-3-Carbinol cu efect citostatic la cancerul de plamin
52 Indole-3-Carbinol un citostatic la aflatoxina B1
care induce carcinogeneza hepatica
53 Indole-3-Carbinol si Diindolylmethane cu efect
anti estrogenic, un citostatic natural
54 Indole-3-Carbinol cu proptietate citostatica inhiba
distrugerea ADN-ului de carcinogeni
55. Broccoli inhiba carcinogeneza la vezica urinara
56 Indole-3-Carbinol si Diindolylmethane induce apoptoza la cancerul cervical
Indole-3-Carbinol si Diindolylmethane induce apoptoza la cancerul cervical
57 Indole-3-Carbinol previne cancerul cervical human la
negi genitali (Human Papilloma Virus) tip 16 (HPV16)
58 Indole-3-Carbinol la papilomatoza laringiana
59. Cresterea de 16 alfa hidroxilat al estradiolului duce la un lupus eritematos sistemic
60. Riscul cresterii maligne la lupus eritematos sistemic
61. Indoli dn Varza (Brassica oleracea) sint anti carcinogenici si imunomodulatori
62 Indole-3-Carbinol un imunomodulator cu finctie imunitara
63 Indole-3-Carbinol inhiba replicarea de herpes simplex
64. Efectul ingestiei de alcol la femei in postmenopauza, cresterea de estrogen cu 300%
65 Indole-3-Carbinol cu efect inhiba neoplazia pulmonara
indusa de nitrosaminele cu specific din tutun la fumatori
66 Indole-3-Carbinol si Diindolylmethane induce
apoptoza la cancerul de prostata
67 Indole-3-Carbinol si sulforafan cu efect la cancerul
de prostata: dihidrotestosteronul (DHT) blocker
Indole-3-Carbinol si Diindolylmethane si sulforafan cu efect la cancerul de prostata: dihidrotestosteronul (DHT) blocker
despre Adenomul de prostata! |
despre Echilibrul hormonal! |
Echilibru hormonal la barbati si femei: Indole-3-Carbinol si Diindolylmethane
Terapia Anti Aging:
Anti-Aging-Systeme
- Formula AntiAging
Bibliografie - References: Indole-3-Carbinol
Informatii din bibliografia electronica la tema: Nutritie si sanatate
1 Auborn KJ, Qi M, Yan XJ, Teichberg S, Chen D, Madaio MP, Chiorazzi N. Lifespan
is prolonged in autoimmune-prone (NZB/NZW) F1 mice fed a diet supplemented
with indole-3-carbinol. North Shore-Long Island Jewish Research Institute, Manhasset,
NY 11030, USA. J Nutr. 2003 Nov;133(11):3610-3.
2. Zeligs MA, Diet and estrogen status: the cruciferous connection. J of
Medicinal Food 1998 Nov 2; 1: 67-82.
3. Carlson DG, Kwolek WF, Williams PH. Glucosinolates in crucifer vegetables:
broccoli, Brussels sprouts, cauliflower, collards, kale, mustard greens,
and kohlrabi. J Amer Soc Hort Sci. 1987;112(1):173-178.
4. Kall, M.A., et al. Effects of dietary broccoli on human drug metabolizing
enzymes : evaluation of caffeine, oestrone and chlorzoxazone metabolism.
Carcinogenesis 1996; 17: 793-799.
5. Verkerk R, Dekker M. Glucosinolates and myrosinase activity in red
cabbage after various microwave treatments. J Agric Food Chem. 2004;52(24):7318-7323.
6 Arneson, DW, Hurwitz, A, McMahon, LM, and Robaugh,
D: "Presence
of 3,3'-Diindolylmethane in human plasma after oral administration of Indole-3-carbinol." Proceedings of the American Association for Cancer Research, 1999 Mar; (40):
2833.
7. Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, Bradlow
HL. Ah receptor binding properties of indole carbinols and induction of hepatic
estradiol hydroxylation. Department of Biochemistry, Queen's University, Kingston,
Ontario, Canada. Biochem Pharmacol. 1993 Mar 9;45(5):1129-36.
8.
Rouzaud G, Young SA, Duncan AJ. Hydrolysis of glucosinolates to isothiocyanates
after ingestion of raw or microwaved cabbage by human volunteers. Cancer
Epidemiol Biomarkers Prev. 2004;13(1):125-131.
9. Verhagen H, et al. 1995.
Reduction of oxidative DNA-damage in humans by brussels sprouts. Carcinogenesis
16:969-70.
10 Arnao MB, et al. 1996. Indole-3-carbinol as a scavenger of free radicals.
Biochem Mol Biol Int 39:1125-34.
11 Shertzer HG, et al. 1988. Intervention in free radical mediated hepatotoxicity
and lipid peroxidation by indole-3-carbinol. Biochem Pharmacol 37:333-38.
12. Gamet-Payrastre L, et al., Selective cytostatic and cytotoxic effects
of glucosinolates hydrolysis products on human colon cancer cells in
vitro. Anti-Cancer Drugs 1998; 9: 141-148.
13. Shapiro TA, Fahey JW, Wade KL,
Stephenson KK, Talalay P. Chemoprotective glucosinolates and isothiocyanates
of broccoli sprouts: metabolism and excretion in humans.
Cancer Epidemiol Biomarkers Prev. 2001;10(5):501-508.
14. Conaway CC, Getahun SM, Liebes
LL, et al. Disposition of glucosinolates and sulforaphane in humans after ingestion
of steamed and fresh broccoli.
Nutr Cancer. 2000;38(2):168-178.
15. Stoewsand GS. Bioactive organosulfur phytochemicals in Brassica oleracea
vegetables-a
review. Food Chem Toxicol 1995;33:537-43.
16. Bradfield CA and Bjeldanes LF, High
performance liquid chromatographic analysis of anticarcinogenic indoles in Brassica
oleracea. J Agric.
Food Chem. 1987; 35:46-49.
17. Verhoeven DT, et al. 1996. Epidemiological studies on brassica vegetables
and cancer risk. Cancer Epidemiol Biomarkers Prev 733-48.
18. Albert-Puleo M. Physiological effects of cabbage with reference to
its potential as a dietary cancer-inhibitor and its use in ancient medicine.
J Ethnopharm.
1983; 9:261-272.
19. Wattenberg LW and Loub WD, Inhibition of polycyclic aromatic hydrocarbon-induced
neoplasia by naturally occurring indoles. Cancer Research 1978; 38:1410-1413.
20 Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF,
Firestone GL. Indole-3-carbinol
inhibits the expression of cyclin-dependent kinase-6 and induces
a G1 cell cycle arrest of human breast cancer cells independent of
estrogen receptor signaling. Department of Molecular and Cell
Biology and Cancer Research Laboratory, University of California,
Berkeley, California 94720, USA. J Biol Chem. 1998 Feb 13;273(7):3838-47.
21 Riby JE, Feng C, Chang YC, Schaldach CM, Firestone GL, Bjeldanes
LF. The
major cyclic trimeric product of indole-3-carbinol is a strong agonist
of the estrogen receptor signaling pathway. Division of Nutritional
Sciences and Toxicology, and Department of Molecular and Cell Biology,
University
of California,
Berkeley, California 94720, USA. Biochemistry. 2000 Feb 8;39(5):910-8.
- Auborn KJ, Fan S, Rosen EM, Goodwin L, Chandraskaren A, Williams
DE, Chen D, Carter TH. Indole-3-carbinol
is a negative regulator of estrogen. North Shore-Long Island
Jewish Research Institute, Manhasset, NY 11030, USA. J Nutr. 2003
Jul;133(7
Suppl):2470S-2475S.
22 Cover CM, Hsieh SJ, Cram EJ, Hong C, Riby JE, Bjeldanes LF, Firestone
GL. Indole-3-carbinol
and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer
cells. Department of Molecular and Cell Biology and The Cancer Research
Laboratory, The University of California at Berkeley, 94720-3200, USA. Cancer
Res. 1999 Mar 15;59(6):1244-51.
23 Ge
X,
Fares FA, Yannai S. Induction
of apoptosis in MCF-7 cells by indole-3-carbinol is independent of p53 and
bax.
Department of Food Engineering and Biotechnology, Technion-Israel Institute
of Technology, Haifa, Israel. Anticancer Res. 1999 Jul-Aug;19(4B):3199-203
24 Niwa
T, Swaneck G, Bradlow HL. Alterations in estradiol metabolism in MCF-7 cells
induced by treatment with indole-3-carbinol and related
compounds.
Steroids. 1994; 59:523-527.
25 Bradlow
HL, et al. 1991. Effects of dietary indole-3-carbinol on estradiol metabolism
and spontaneous mammary tumors in mice. Carcinogenesis 12:1571-74.
- Bradlow HL, Michnovicz J, Telang NT, Osborne MP. Effects of dietary indole-3-carbinol
on estradiol metabolism and spontaneous mammary tumors in mice. Institute for
Hormone Research, New York, NY 10016. Carcinogenesis. 1991 Sep;12(9):1571-4.
26. Colditz GA. Estrogen, estrogen plus progestin
therapy, and risk of breast cancer. Channing Laboratory, Department of Medicine,
Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115.
USA. Clin Cancer Res. 2005 Jan 15;11(2 Pt 2):909s-17s.
27.Beresford SA, Weiss NS, Voigt LF, McKnight B. Risk of endometrial cancer
in relation to use of oestrogen combined with cyclic progestagen therapy in
postmenopausal
women. Departments of Epidemiology, University of Washington, Seattle 98195-7236,
USA. Lancet. 1997 Feb 15;349(9050):458-61.
- Beral V, Bull D, Reeves G; Million Women Study Collaborators. Endometrial cancer
and hormone-replacement therapy in the Million Women Study. Lancet. 2005 Apr
30-May 6;365(9470):1543-51.
28. Sturdee DW, Ulrich LG, Barlow DH, Wells M, Campbell MJ, Vessey MP, Nielsen
B, Anderson MC, Bragg AJ. The endometrial response to sequential and continuous
combined oestrogen-progestogen replacement therapy. Women's Health Unit, Birmingham
Heartlands and Solihull Hospital NHS Trust, West Midlands, UK. BJOG. 2000 Nov;107(11):1392-400.
- Sturdee DW, Ulrich LG, Barlow DH, Wells M, Campbell MJ, Vessey MP, Nielsen
B, Anderson MC, Bragg AJ. The endometrial response to sequential and continuous
combined oestrogen-progestogen replacement therapy. Women's Health Unit, Birmingham
Heartlands and Solihull Hospital NHS Trust, West Midlands, UK. BJOG 2001 Mar;108(3):335.
29.
Beral V; Million Women Study Collaborators, Bull D, Green J, Reeves G. Ovarian
cancer and hormone replacement therapy in the Million Women Study.
Million Women Study Coordinating Centre, Cancer Research UK Epidemiology Unit,
Richard Doll Building, Roosevelt Drive, Oxford, OX3 7LF, UK. Lancet. 2007 May
19;369(9574):1703-10.
30. Rossouw JE, Prentice RL, Manson JE, Wu L, Barad D, Barnabei VM, Ko M, LaCroix
AZ, Margolis KL, Stefanick ML. Postmenopausal hormone therapy and risk of cardiovascular
disease by age and years since menopause. Women's Health Initiative Branch,
National Heart, Lung, and Blood Institute, Bethesda, Md 20892, USA. JAMA. 2007
Apr 4;297(13):1465-77.
31 Telang
NT, et al., Inhibition of proliferation and modulation of estradiol metabolism:
novel mechanisms for breast
cancer prevention by the phytochemical
indole-3-carbinol. Proceedings of the Society for Experimental
Biology and Medicine 1997; 216: 246-252.
32 Bradlow
HL, Sepkovic DW, Telang NT, Osborne MP. Multifunctional aspects of the action
of indole-3-carbinol as an antitumor agent.
Ann NY Acad Sci. 1999;
889:204-213.
33. Ho GH, et al. Urinary 2/16 alpha-hydroxyestrone ratio: correlation
with serum insulin-like growth factor binding protein-3 and a potential
biomarker of breast cancer risk. Ann Acad Med Singapore 1998; 27:294-299.
34. Bradlow HL, et al., 16a hydroxylation of estradiol: a possible risk
marker for breast cancer. Annals NY Acad. Sci. 1986; 464: 138-151.
35. Sepkovic DW, et al., Estrogen metabolite ratios and risk assessment
of hormone related cancers: assay validation and prediction of
cervical cancer risk. Annals of the N.Y. Acad. of Science 1995; 768: 312-316.
36 Kojima
T., et al., Chemoprevention of spontaneous endometrial cancer in female donryu
rats by dietary indole-3-carbinol. Cancer
Research 1994;
54: 1446-1449.
37. Fishman, J,
et al., Increased estrogen -16-hydroxylase activity in women
with breast and endometrial cancer. Journal of Steroid Biochem. and Mol. Biol.
1984; 20: 1077-1081.
38 Michnovicz
JJ. 1998. Increased estrogen 2- hydroxylation in obese women using
oral indole-3-carbinol. Int J Obes Relat Metab Disord 22:227-9.
39. Hershcopf RJ, Bradlow HL. Obesity, diet, endogenous estrogens,
and the risk of
hormone-sensitive cancer. Am J Clin Nutr. 1987 Jan;45(1 Suppl):283-9.
40. Carruba G, Granata OM, Pala V, et al. A traditional Mediterranean
diet decreases endogenous estrogens in healthy postmenopausal women.
Nutr Cancer. 2006;56(2):253-9.
41. Wu M, Harvey KA, Ruzmetov N, et al. Omega-3 polyunsaturated fatty acids
attenuate breast cancer growth through activation of a neutral sphingomyelinase-mediated
pathway. Int J Cancer. 2005 Nov 10;117(3):340-8.
42.
Bhat KP, Pezzuto JM. Resveratrol exhibits cytostatic and antiestrogenic properties
with human endometrial adenocarcinoma
(Ishikawa) cells. Program for Collaborative Research in the Pharmaceutical
Sciences and Department of Medicinal Chemistry and Pharmacognosy, College
of Pharmacy, University
of Illinois at Chicago, Chicago, Illinois 60612, USA. Cancer Res. 2001
Aug 15;61(16):6137-44.
43. Lu, R., and Serrero, G. Resveratrol, a natural product derived from grape,
exhibits antiestrogenic activity and inhibits the growth of human breast
cancer cells.
J. Cell. Physiol., 179: 297–304, 1999.
44. Matsumura A, Ghosh A, Pope GS, Darbre PD. "Comparative
study of oestrogenic properties of eight phytoestrogens in MCF7 human breast
cancer cells." J Steroid Biochem Mol Biol. 2005 Apr;94(5):431-43.
45. Bhat KP, Lantvit D, Christov K, Mehta RG, Moon RC, Pezzuto JM. Estrogenic
and antiestrogenic properties of resveratrol in mammary tumor models. Program
for
Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal
Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois
at Chicago, Chicago, Illinois 60612, USA. Cancer Res. 2001 Oct 15;61(20):7456-63.
46. Le Bail, J. C., Champavier, Y., Chulia, A. J., and Habrioux, G. Effects
of phytoestrogens on aromatase, 3β and 17β-hydroxysteroid dehydrogenase activities
and human
breast cancer cells. Life Sci., 66: 1281–1291, 2000.
47. Gehm BD, McAndrews JM, Chien PY, Jameson JL. Resveratrol, a polyphenolic
compound found in grapes and wine, is an agonist for the estrogen receptor.
Division
of Endocrinology, Metabolism and Molecular Medicine, Northwestern University
Medical School, 303 E. Chicago Avenue, Chicago, IL 60611, USA. Proc Natl
Acad Sci U S A. 1997 Dec 9;94(25):14138-43.
48. Bowers JL, Tyulmenkov VV, Jernigan SC, Klinge CM. Resveratrol acts as a
mixed agonist/antagonist for estrogen receptors alpha and beta. Department
of Biochemistry
and Molecular Biology, University of Louisville School of Medicine, Kentucky
40292, USA. Endocrinology. 2000 Oct;141(10):3657-67.
- Levenson AS, Gehm BD, Pearce ST, Horiguchi J, Simons LA, Ward JE 3rd, Jameson
JL, Jordan VC. Resveratrol acts as an estrogen receptor (ER) agonist in breast
cancer cells stably transfected with ER alpha. Robert H Lurie Comprehensive
Cancer Center, The Feinberg School of Medicine, Northwestern University, Chicago,
IL
60611, USA. Int J Cancer. 2003 May 1;104(5):587-96.
49. Potter GA, Patterson LH, Wanogho E, Perry PJ, Butler PC, Ijaz T, Ruparelia
KC, Lamb JH, Farmer PB, Stanley LA, Burke MD. The cancer preventative agent
resveratrol is converted to the anticancer agent piceatannol by the cytochrome
P450 enzyme
CYP1B1. Cancer Drug Discovery Group, School of Pharmacy, De Montfort University,
The Gateway, Leicester LE1 9BH, UK. Br J Cancer. 2002 Mar 4;86(5):774-8.
50 Grubbs
CJ, et al. 1995. Chemoprevention of chemically-induced mammary carcinogenesis
by indole-3-carbinol. Anticancer Res 15:709-16.
51 Kassie
F, Anderson LB, Scherber R, Yu N, Lahti D, Upadhyaya P, Hecht SS. Indole-3-carbinol
inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced
lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations
in protein levels. Cancer Center, University of Minnesota, Minneapolis, Minnesota
55455, USA. Cancer Res. 2007 Jul 1;67(13):6502-11.
52 Manson,
M.M., Hudson, E.A., Ball, H.W., Barrett, M.C., Clark, H.L.,
Judah, D.J., Verschoyle, R.D. and Neal, G.E.
(1998) Chemoprevention
of aflatoxin
B1-induced carcinogenesis by indole-3-carbinol in rat liver
- predicting the outcome using early biomarkers. Carcinogenesis,
19, 1829-36.
53 Chang
YC, Riby J, Chang GH, Peng BC, Firestone G, Bjeldanes LF.
Cytostatic
and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane,
a major
in vivo product of dietary indole-3-carbinol. Division of
Nutritional Sciences and Toxicology, University of California, Berkeley
94720, USA. Biochem Pharmacol.
1999 Sep 1;58(5):825-34.
54 He
YH, et al. 1997. Chemopreventive properties of indole-3-carbinol
(I3C): inhibition of DNA adduct formation
of the dietary carcinogen, 2-amino-1-methyl-6-pehnylimidazo
[4,5-b]pyridine (PhIP), in female F344 rats. J Cell Biochem
Suppl
27:42-51.
55.
Munday R, Mhawech-Fauceglia P, Munday CM, Paonessa JD, Tang
L, Munday JS, Lister C, Wilson P, Fahey JW, Davis W, Zhang
Y. Inhibition of urinary bladder carcinogenesis
by broccoli sprouts. AgResearch Limited, Ruakura Agricultural Research Center,
Hamilton, New Zealand. Cancer Res. 2008 Mar 1;68(5):1593-600. Epub 2008 Feb
29.
56 Chen
DZ, Qi M, Auborn KJ, Carter TH. Indole-3-carbinol and diindolylmethane induce
apoptosis of human cervical
cancer cells and in murine HPV16-transgenic preneoplastic
cervical epithelium. North Shore-Long Island Jewish
Research Institute, Manhasset, NY 11030, USA.
J Nutr. 2001 Dec;131(12):3294-302.
57 Jin
L, Qi M, Chen DZ, Anderson A, Yang GY, Arbeit JM,
Auborn KJ. Indole-3-carbinol
prevents cervical cancer in human papilloma virus
type 16 (HPV16) transgenic mice. Department of Otolaryngology,
Long Island Jewish Medical Center, The Long Island
Campus of Albert
Einstein College of Medicine,
New Hyde
Park, New York 11040, USA.
Cancer Res. 1999 Aug 15;59(16):3991-7.
58 Rosen
CA, Woodson GE, Thompson JW, Hengesteg AP, Bradlow HL. Preliminary
results of the use of indole-3-carbinol for recurrent
respiratory papillomatosis.
Department of Otolaryngology--Head and Neck Surgery,
University of Pittsburgh Medical Center, Pennsylvania,
USA. Otolaryngol
Head Neck
Surg. 1998 Jun;118(6):810-5.
59. Lahita, RG, et al., Increased 16a-hydroxylation
of estradiol is systemic lupus erythematosus. J. Clin. Endocrinol.
Metab. 1981; 53: 174-178.
60. Ramsey-Goldman R, et al., Increased risk of malignancy
in patients with systemic lupus erythematosus. J. of Investigative
Medicine 1998; 46:217-222.
61. Preobrazhenskaya
MN, Bukhman VM, Korolev AM, Efimov SA, "Ascorbigen
and other indole-derived compounds from Brassica vegetables
and their analogs as anticarcinogenic and immunomodulating agents." Pharmacol
Ther. 1993 Nov;60(2):301-13.
62 Exon
JH, South EH, "Dietary
indole-3-carbinol alters immune functions
in rats." J Toxicol Environ Health A. 2000 Feb 25;59(4):271-9.
63 Stoner
TD, Sweet TJ, Fu MM, Delucia AL, Docherty JJ. Indole-3-Carbinol Inhibits Herpes
Simplex Virus Replication. Interscience Conference on Antimicrobial
Agents and Chemotherapy, presentation number V-287.
64. E. S. Ginsburg, N. K. Mello, J. H. Mendelson, R. L. Barbieri, S. K. Teoh,
M. Rothman, X. Gao and J. W. Sholar Effects
of alcohol ingestion on estrogens in postmenopausal women Department of
Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA 02115,
USA. JAMA Vol. 276 No. 21, December 4,
1996; 276:1747-51.
65 Morse
MA, LaGreca SD, Amin SG, Chung FL. Effects of indole-3-carbinol on lung
tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
(NNK) and on the metabolism
and disposition of NNK in A/J mice. Section of Nucleic Acid Chemistry, Naylor
Dana Institute for Disease Prevention, American Health Foundation, Valhalla,
New York. Cancer Res. 1990 May 1;50(9):2613-7.
66 Nachshon-Kedmi
M, Yannai S, Haj A, Fares FA. Indole-3-carbinol and 3,3'-diindolylmethane induce
apoptosis in human prostate cancer cells.
Faculty of Food Engineering and Biotechnology, Technion- Israel Institute of
Technology, 32000, Haifa, Israel. Food Chem Toxicol. 2003 Jun;41(6):745-52.
67 Frydoonfar
HR, McGrath DR, Spigelman AD. The effect of indole-3-carbinol and sulforaphane
on a prostate cancer cell line. Discipline of Surgical Science,
Faculty of Health, The University of Newcastle, New South Wales, Australia.
ANZ J Surg. 2003 Mar;73(3):154-6.
Parerea din pasajele acestui site nu a fost independent cercetate sau confirmate
|
Anti-Aging-Systeme
© 2008
|
Design by NB |