Isoprinosine Antiviral
Isoprinosine Antiviral
Isoprinosine imunomodulator
Inosine - Hipoxantina Riboside este un nucleotid care se gaseste in
tesutul muscular
Studiile stiintifice au aratat ca Inosine (Hipoxantina Riboside) creste
productia de Adenozintrifosfat ATP - Este un precursor al adenozinei
1 Isoprinosine un imunomodulator si antiviral.
2 Studiile
de la Institutul de Medicina Sportiva din Bucuresti, au aratat efectele inosinei
la sportivii de haltere.
3 Efectul
de Inosine cu performanta la testarea de efort pe banda rulanta.
4 Efectul
de Suplimente nutritive cu Inosine la performanta ciclica aeroba si anaeroba
- creste capacitatea de transport a oxigenului in in tesuturi pentru
marirea energiei
5 Inosine promoveaza producerea de 2,3 difosfoglicerat
(2,3DPG) are afinitate la hemoglobina cu functie
transport a oxigenului de celulele rosii in tesuturi pentru marirea
energiei si stabilizare a deoxihemoglobina
6 Inosine inhiba producerea de citokine inflamatorii
7 Efectul
de Inosine dupa infuzia de contrykal si heparina in varietatea tipurilor hemodinamice
la ischemia miocardica
8 Efectul
de Inosine in glicoliza si contractia in timpul ischemiei miocardice
9 Inosine
indicat la infarctul miocardic, studiu clinic
10 Efectul
de Inosine - Hipoxantina
Riboside un nucleotid la activitatea miocardica
11 Efectul
de Inosine la metabolismul adenin nucleotid cardiac
12 Efectul
terapeutic de Inosine in sindromul Tourette
13 Inosine
in tratamentul de scleroza multipla
14 Inosine
stimuleaza cresterea axonala in cortico–spinal dupa o leziune
15 Inosine
stimuleaza cresterea axonala si
inbunatateste rezultatul dupa atacul vascular cerebral ischemic
16 Inosine
impreuna cu acid p-aminobenzoic PABA se formeaza natural in organism
- Isoprinosine un imunomodulator si antiviral
Isoprinosine un imunomodulator si antiviral
17 Isoprinosine
cu efect in restaurarea imunitatii la persoanele in virsta
18 Isoprinosine
cu actiune anti herpes
19 Isoprinosine:
Evaluare clinica si imunologica la HIV+
20 Isoprinosine:
Studiu de un an de eficacitate si siguranta la infectia HIV/SIDA (Sindromul
Imunodeficientei Umane Dobandite)
21 Isoprinosine
cu eficacitate in infectia HIV/SIDA (Sindromul Imunodeficientei
Umane Dobandite)
22 Isoprinosine:
Evaluarea in infectia umana de rino-virus
23 Isoprinosine la tratamentul avansat de cancer colorectal
24 Restaurarea
imunitara cu Isoprinosine la copii cu infectie respiratorie
25 Isoprinosine
ca adjuvant in terapia de cancer la nivelul bronhiilor, studiu randomizat dublu
orb placebo controlat
26 Isoprinosine
in tratamentul de cancer colorectal
27 Isoprinosine
in tratamentul de alopecie areata
Stiinta ingrijirii parului: Terapia cu PABA si Inosine = Isoprinosine
28 Isoprinosine
studiu clinic si imunologic la alopecia areata si alopecia universalis
Alopecie - caderea parului (alopecia areata)
- O boala autoimmuna la care este afectat sistemul imunitar (celulele albe)
Limfocitele -T ataca foliculele de par
- Controlul functiei celulelor T de neurotrofine (polipeptide),
in pielea afectata de alopecie - caderea parului (alopecia
areata)
Factorul de crestere nervoasa (NGF) un polipeptid din
familia de neurotrofine
Alopecie totala (alopecia totalis)
Alopecie universala (alopecia universalis)
| Bibliografie-Referinte: |
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| Informatii din bibliografia electronica la tema: Nutritie si sanatate |
1 Renoux G, Renoux M, Guillaumin
JM. Isoprinosine
as an immunopotentiator.J Immunopharmacol. 1979;1(3):337-56.
2 Dragan
I, Baroga M, Eremia N, Georgescu E. Studies
regarding some effects
of inosine in elite weightlifters.Institute of Sports Medicine, Bucharest,
Romania.Rom
J Physiol. 1993 Jan-Jun;30(1-2):47-50.
3 Williams
MH, Kreider RB, Hunter DW, et al. Effect of inosine supplementation on 3-mile
treadmill run performance
and VO2 peak. Med Sci Sports Exec. 1990;
22:517-522.
4 Starling
RD, Trappe TA, Short KR, Sheffield-Moore M, Jozsi AC, Fink WJ, Costill DL.
Effect
of inosine supplementation on aerobic and anaerobic cycling performance.
Human Performance Laboratory, Ball State University, Muncie, IN 47306, USA.
Med Sci Sports Exerc. 1996 Sep;28(9):1193-8.
5 Kovacevic
et al., "Interaction of Metabolism of Aspartate and Inosine and Energy State of Human
Cells," Biochem. J.: 247, 47, 1987
6 Hasko
G, Kuhel DG, Nemeth ZH, Mabley JG, Stachlewitz RF, Virag L, Lohinai
Z, Southan GJ,
Salzman AL, Szabo C. Inosine
inhibits inflammatory cytokine production by a posttranscriptional
mechanism
and protects against endotoxin-induced shock. Inotek Corp., Beverly, MA 01915,
USA. ghasko@inotekcorp.com J Immunol. 2000 Jan 15;164(2):1013-9.
7 Korotkov
AA, Zhorzholiani TD, Chkheidze LG, Shalamberidze DN. Effect
of inosine after early infusion of contrykal and heparin in various hemodynamic
types
of acute myocardial ischemia Kardiologiia. 1988 Oct;28(10):91-4.
8 Lewandowski
ED, Johnston DL, Roberts R. Effects
of inosine on glycolysis and
contracture during myocardial ischemia. Department of Medicine, Baylor College
of Medicine, Houston, TX 77030. Circ Res. 1991 Feb;68(2):578-87.
9 Kipshidze
NN, Korotkov AA, Chapidze GE,
Marsagishvili LA, Todua EI. Indications
for the use of inosine in myocardial infarct a clinical and experimental study.
Kardiologiia.
1978 Mar;18(3):18-28.
10 Faucon
G, Lavarenne J, Collard M, Evreux
JC. Effects
of a nucleoside, hypoxanthine-d-riboside,
on myocardial activity and irrigation Therapie. 1966 Sep-Oct;21(5):1239-52.
11 Zimmer
HG. Effect
of inosine on cardiac adenine nucleotide metabolism in rats. Adv Myocardiol.
1985; 6:173-183.
12Cheng
Y, Jiang DH. Therapeutic effect of inosine in Tourette syndrome and
its possible mechanism of action. Dept. of Neurol. Tianjin Medical College
Hosp. Zhonghua
Shen Jing Jing Shen Ke Za Zhi. 1990 Apr;23(2):90-3, 126-7.
13 Koprowski
H, Spitsin SV, Hooper DC. Prospects for the treatment of multiple sclerosis by
raising serum levels of uric acid,
a scavenger of peroxynitrite. Ann Neurol 2001;49:139.
14 Benowitz,
L.I., et al. 1999. Inosine stimulates extensive axon collateral growth in the
rat corticospinal tract after
injury. Proceedings of the National Academy of Sciences 96(Nov. 9):13486-13490.
15 Chen,
P., L. I. Benowitz, et al. 2002. Inosine
induces axonal rewiring and improves behavioral outcome after stroke. Proceedings
of the National Academy of Sciences 99(June 25):9031-9036.
16 Renoux
G, Renoux M, Guillaumin JM. Isoprinosine
as an immunopotentiator.J Immunopharmacol. 1979;1(3):337-56.
17 Tsang
KY, Pan JF, Swanger DL, Fudenberg HH. In
vitro restoration of immune responses in aging humans by isoprinosine.
Int J Immunopharmacol. 1985;7(2):199-206.
18 Paul
Gordon,1 Bruce Ronsen, and Eric
R. Brown Anti-Herpesvirus
Action of Isoprinosine. Departments of Pharmacology and Microbiology, Chicago
Medical School, University of Health Sciences, Chicago, Illinois 60612. Antimicrob
Agents Chemother. 1974 February; 5(2): 153–160.
19De
Simone C, Albertini F, Almaviva M, Angarano G, Chiodo F, Costigliola P, Delia
S, Ferlini A, Gritti F, Mazzarello
G, et al. Clinical
and immunological assessment in HIV+ subjects receiving inosine-pranobex. A
randomised, multicentric study. Insegnamento Malattie Infettive, Universita,
L'Aquila, Italia. Med Oncol Tumor Pharmacother. 1989;6(1):63-7.
20Thorsen
S, Pedersen C, Sandstrom E, Petersen CS, Norkrans G, Gerstoft J, Karlsson A,
Christensen KC, Hakansson
C, Pehrson PO, et al. One-year
follow-up on the safety and efficacy of isoprinosine for human immunodeficiency
virus infection. Scandinavian Isoprinosine Study Group. Department of Infectious
Diseases, Hvidovre Hospital, Copenhagen, Denmark. J Intern Med. 1992 Jun;231(6):607-15.
21 Pedersen
C, Sandstrom E, Petersen CS, et al. The
efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome
in patients with human immunodeficiency virus infection. The Scandinavian
Isoprinosine Study Group. N Engl J Med. 1990;322:1757-1763.
22 Donald
M. Pachuta, Yasushi Togo, Richard B. Hornick, Andrew R. Schwarts,1 and Suketami
Tominaga.Evaluation
of Isoprinosine in Experimental Human Rhinovirus Infection. Antimicrob Agents
Chemother. 1974 April; 5(4): 403–408.
23 Colozza
M, Tonato M, Belsanti V, et al. 5-Fluorouracil and isoprinosine in the treatment
of advanced colorectal cancer. A limited phase I, II evaluation.
Cancer. 1988;15:1049-1052.
24 Wiedermann
D, Wiedermannova D, Lokaj J. Immunorestoration
in children with
recurrent respiratory infections treated with isoprinosine. Department of
Pathological Physiology, Medical Faculty, J.E. Purkyne University, Brno, Czechoslovakia.
Int
J Immunopharmacol. 1987;9(8):947-9.
25 Roeslin
N, Dumont P, Morand G, Wihlm JM, Witz JP. Immunotherapy
as an adjuvant to surgery in carcinoma of bronchus. Results in
three randomised trials. Department of Thoracic Surgery, C.H.U. de
Strasbourg, France.
Eur J Cardiothorac Surg. 1989;3(5):430-5.
26Colozza
M, Tonato M, Belsanti V, Mosconi AM, Fiorucci S, Gernini I, Rambotti P, Davis
S. 5-Fluorouracil
and isoprinosine in the treatment of advanced colorectal cancer.
A limited phase I, II evaluation. Division Di Oncologia Medica,
Policlinico-Universita' Perugia, Italy. Cancer. 1988 Sep 15;62(6):1049-52.
27Thiers
BH. Isoprinosine treatment of alopecia areata. Department of Dermatology,
Medical University
of South Carolina, Charleston 29425-2215. J Invest Dermatol.
1991 May;96(5):72S-73S.
28 Lowy
M, Ledoux-Corbusier
M, Achten G, Wybran J. Clinical
and immunologic response to Isoprinosine in alopecia areata and alopecia
universalis: association
with autoantibodies. J Am Acad Dermatol. 1985 Jan;12(1 Pt 1):78-84.
Parerea din pasajele acestui site nu a fost independent cercetate sau confirmate.
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Inosine 200 mg impreuna cu acid p-aminobenzoic PABA 500 mg se formeaza natural in organism Isoprinosine un imunomodulator si antiviral.
