Procesul de imbatranire cu cauzele endogene si exogene
1. Teoria radicalilor liberi in procesul de imbatrinire
- Radicalii liberi considerati ca mediatori
patologici.
- Formarea de radicali liberi prin: Factorii
exogeni ca poluarea aerului, razele-UV, radiatii ionizante, etc., factorii
endogeni pot fi stres, exercitiu fizic extenuant, inflamatii, fumat, etc.
- Tipuri de radicali liberi: Radicalii liberi
ai oxigenului, Radicalii liberi ai azotului, Radicalul thiil,etc
Formarea de radicali
liberi
Structura celulei
este oxidata de actiunea agresiva a radicalilor liberi
- Inalta concentratie de oxigen reactiv
- radicalii liberi si cantitatea insuficienta in organism de antioxidanti,
genera in organite (centrale energetice celulare) eficacitatea scazuta a
repararii ADN-ului, ca rezultat: Disfunctia mitocondriala, care este o caracteristica
a celulelor maligne.
Distrugerile
ADN-ului de radicalii liberi care produc stres oxidativ
- Mutatiile ADN-ului de radicalii liberi afecteaza energia celulara
ATP Administrarea de antioxidanti ca factor anti cancer determina reversia
fenotipului malign prin inhibarea celulelor de cancer - Anti cancer: EGCG Galatul de epigalocatechina
Degradarea ADN-ului
prin acumularea de 8-hidroxi-2’-deoxiguanozina
Reversia fenotipului
malign prin inhibarea celulelor de cancer
Despre antioxidanti: Antioxidantii sint
molecule care apara organismul de efectele oxigenului reactiv - Radicalii
liberi
Radicalii liberi produc stres oxidativ, iar antioxidantii apara celula de
radicalii liberi care sint molecule instabile, contin electroni neimperecheati,
adica un electron ocupa un singur orbital.
- Antioxidanti se gasesc in orice celula,
protejeaza organismul de distrugerile provocate la nivel celular de radicalii
liberi.
- Antioxidantii pot neutraliza radicalii liberi limitind distrugerea provocata,
daca suficienti antioxidanti sint involvati - Capacitate suficienta antioxidativa
- Acid Alfa Lipoic prin proprietati si functie regenereaza alti antioxidanti
ca: Vitamina C, Vitamina E, Glutation, Coenzima Q10 ofera protectie antioxidativa
de efectele radicalilor liberi.
Antioxidantii protejind
celula de radicalii liberi - Capacitate suficienta
Sint o multime de antioxidanti in extracte de plante naturale,
fitofarmaceutice, nutraceutice cu capacite de neutralizare a radicalilor
liberi Antioxidanti cheie: Acid Alfa Lipoic, Coenzima Q10, Vitamine: Vitamina
C, Vitamina E, Caretenoizi, (beta caroten,alfa caroten, licopen, luteina,
zeaxantina) Compusi fenolici: Flavonoizi, polifenoli care confera protectie
ridicata antoxidativa
- Suficienti
antioxidanti de recomandat: Acid Alfa Lipoic, Ceai Verde EGCG, Vitamina C, Glutation, Vitamin E, Carotenoizi, Coenzima Q10 sau enzime antioxidante ca superoxid dismutaza (SOD) care detoxifica radicalul superoxid,
peroxidul de hidrogen (H 2O2) si Glutation peroxidaza (GPx) care detoxifica peroxizii celulari
- Spirulina contine superoxid
dismutaza (SOD) un antioxidant puternic 110000 Unitati/100g
- Vitamina E este un important antioxidant solubil in grasime, reduce oxidarea
lipoproteinelor cu densitate joasa LDL, previne initierea si progresia de ateroscleroza.
- Carotenoizi sint fito-nutrienti impiortanti solubili in grasime ca: Alfa caroten,
Beta caroten, Licopene, Luteina, Zeaxantina, Astaxantina.
- Carotenoizi joaca un rol important ca fotoprotectia solara, trebuie sa asiguram
pielii noastre fotoprotectia necesara.
- Compusi fenolici cu proprietaţi antiseptice, antibiotice, antifungice, antivirale.
- Compusi fenolici pot fi solubil in apa sau grasime ca: Hidroxitirosol cel
mai puternic antioxidant din Uleiul de Masline sau capsunii sint compusi
fenolici.
- Coenzima Q10 ca antioxidant in mitocondria si celule cu protectie de peroxidarea
lipidica, CoQ10 reduce oxidarea si leziunea ADN in limfocite.
- Coenzima Q10 cu activitate in mitocondria: Activeaza producerea de Adenozintrifosfat
(ATP)
- Coenzima Q10 ca stabilizator in membrana celulara asigura permeabilitatea membranei
celulare pentru ca substantele vitale
sa poata intra in celula.
- Scaderea concentratiei de Coenzima Q10, pe masura imbatranirii cu pina la 60%
5. Coenzima Q10 cu activitate in mitocondrii: Mitocondria uzina energetica de adenozintrifosfat (ATP) a materiei
vii, activeaza producerea de adenozintrifosfat (ATP)
Coenzima Q10 cu activitate in
mitocondrii: Mitocondria uzina energetica de adenozintrifosfat (ATP)
a materiei vii, activeaza producerea de adenozintrifosfat (ATP)
6. Coenzima Q10 ca antioxidant in mitocondrii si celule cu protectia
de peroxidare lipidica, CoQ10 reduce oxidarea si leziunea ADN in limfocite
7. Coenzima Q10 cu potential de tratament in disfunctie
mitocondriala si dauna oxidativa de radicalii liberi in boala Alzheimer si
Parkinson
Creier sanatos
Creier cu
Alzheimer
- Coenzima Q10 este o substanta vitala,
un antioxidant puternic, neutralizeaza radicalii liberi, ajuta la preintampinarea
efectelor toxice exercitate de multe medicamente sintetice
8. Ceai Verde Supreme cu: Polifenoli, catehine si extr.Epigalocatehingalat
(EGCG) are activitate antioxidanta de neutralizare a radicalilor liberi: radicalul
superoxid(O2-), radicalul peroxil(RO2-), radicalul peroxinitrit(OONO -), peroxid de hidrogen(H2O2) previne oxidarea LDL - biologia si medicina radicalilor liberi
9. Ceai Verde cu: Polifenoli, catehine si extr. Epigalocatehingalat
(EGCG) are activitate antioxidanta de neutralizare a radicalilor liberi, inhiba peroxidarea
lipidelor, degradarea ADN-ului, in 8-hidroxi-2’-deoxiguanozina (8-OHdG), este un biomarker a stresului oxidativ, acumulata in
ADN cauzeaza disfunctia mitocondriala si criza energetica
10. Ceai Verde Supreme un produs natural fotoprotector
protejaza pielea de radiatiile UV, cu activitate antioxdanta si imunomodulatoare
EGCG un produs natural fotoprotector
protejaza pielea
11. Ceai Verde cu: Polifenoli, catehine si extr. Epigalocatehingalat (EGCG) antioxidant puternic un inhibitor enzimei de telomeraza
EGCG cu capacitate de absorbtie a
radicalului liber a oxigenului - ORAC, comparatia valorilor fata de Vitamina
C
12. Ceai Verde cu: Polifenoli, catehine si extr. Epigalocatehingalat (EGCG) are actiune antioxidanta reduce placa aterosclerotica, meta analiza
13. Ceai Verde cu: Polifenoli, catehine si
extr. Epigalocatehingalat (EGCG) in efectul de productie de citokine proinflamatorii si anti inflamator
Nutraceutice - Nutraceuticele Anti Aging Systeme sint din plante naturale: Farmacia
Naturala, care au efecte farmaceutice numite si fitofarmaceutice.
Quercitina cu: Flavonoizi, Polifenoli 95% din:
Farmacia Naturala
Quercetin cu activitate: antioxidanta,
anti-inflammatorie, antivrala, immunomodulatoare, anti cancer, gastroprotectiva,
anti alergica si in prevenirea de complicatii ale diabetului.
14. Quercetina un bioflavonoid
cu proprietati antioxidante
Quercetina cu capacitate de absorbtie a radicalului
liber a oxigenului - ORAC, comparatia valorilor fata de Vitamina C
15. Quercetina un antioxidant puternic inhiba prooxidante ca xantin oxidaza si activitatea
xantin dehidrogenaza
16. Quercetina supliment nutritional
cu actiune antioxidanta la estrogeni si fitoestrogeni
17. Quercetina si Rutina cu actiune de chelatizare
si antioxidanta in peroxidarea lipidica
18. Quercetina si metabolitii
epicatechin ca EGCG participa ca antioxidanti in plasma sanguina
19. Quercetina
si Vitamina C cu efect protector de stresul oxidativ indus in neuro degenerare
Extract din Samburi de Struguri (Vitis Vinifera)
OPC extr. stand. 95%
20. Extract din Samburi de Struguri - OPC in practica, flavonoide si aplicatia lor
exercita actiune anti inflamatoare, anti artritic, anti alergic, previne
inbatrinirea dermei, activitate antioxidanta de neutralizare a radicalilor
liberi si inhibare razelor UV
OPC 95% cu capacitate de absorbtie a radicalului
liber a oxigenului - ORAC, comparatia valorilor fata de Vitamina C
21. Acidul elagic reduce stresul oxidativ
22. Acid Elagic cu actiune de antioxidant
si la procesul de peroxidare lipidica
23. Acid Elagic cu efect protectiv la stresul oxidativ
produs de celulele PC12.
24. Capsaicina
cu activitate antioxidanta
Capsaicina cu activitate antioxidanta
25. N-Acetilcisteina efect protectiv la plamin
de peroxidarea lipidica, previne sindromul de detresa respiratorie indus de
dauna oxidativa a radicalilor liberi
N-Acetilcisteina efect protector la
plamin
26. N-Acetilcisteina ca antioxidant in tratamentul
de citostatica la cancer
N-Acetilcisteina cu capacitate de absorbtie a
radicalului liber a oxigenului - ORAC, comparatia valorilor fata de Vitamina
C
27. N-Acetilcisteina cu actiune antioxidanta in
reactia cu radicalii liberi
28. Acid Alfa Lipoic, este un puternic antioxidant
de 40-60 ori ca Vitamina E, cu actiune de reciclare a altor antioxidanti, cu
activitate antioxidanta de neutralizare a radicalilor liberi.
- Acid Alfa Lipoic (AAL) este un
di-sulfid, numit si acid tioctic sau lipoate poate regenera antioxidanti
ca: Glutationul oxidat la glutation redus, Coenzima Q10, Vitamina C, Vitamina
E, Glutationul disulfid, Cistina in Cisteina, Tioredoxina oxidata la Tioredoxina
redusa importanta care leaga factori de transcriptie de ADN.
29. Antioxidanti reduc nivelul
de F-2 isoprostan, un biomarker a stresului oxidativ, neutralizeaza radicali
liberi* hidroxil (OH) , radicali oxidului nitric (NO), peroxinitrit (OONO -), peroxidul de hidrogen (H2O2), oxigenul singlet (1-O2), etc.
Isoflavone din Pueraria cu actiune:
Antioxidanta
Resveratrol un polifenol din grupa fito-alexinelor.
- Resveratrol combate bolile pe: Calea naturala - Medicina naturala
- Resveratrol face parte din clasa de: Polifenoli, subclasa Stilbene (trans-3,5,4'-trihydroxystilbene)
- Resveratrol este sintetizat din p-cumaroil CoA si malonil CoA.
- Recunoscut ca antioxidant care raspunde la: Stres, infectii de fungi, si
radiatii ultraviolete (UV)
32. Resveratrol un antioxidant natural cu cu eficienta de actiune in oxidarea
in lipozom
Resveratrol un antioxidant natural cu cu eficienta
de actiune in oxidarea
in lipozom
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Literatura
- Chemistry
and Applications of Green Tea by Takehiko Yamamoto, Lekh Raj Juneja,
Djoing-Chi Chu, Mujo Kim, L.R. Juneja, D.C. Chu, M. Kim
Parerea din pasajele acestui site nu a fost independent cercetate sau confirmate.
Ceai
Verde (Camellia Sinensis)
Regnul:
Plantae - Planta
Increngatura:
Traheofitelor - Planta vasculara
Subincrengatura:
Spermatofita - Planta cu saminta
Clasa:
Angiosperme - Dicotiledonate - Embrion
Subclasa:
Dillenidae
Ordinea:
Theales
Familia:
Theaceae
Genul:
Camellia L.
Specia:
Camellia Sinensis L. - Ceai Verde
despre Antioxidant,
antioxidanti: Antioxidantii fanatana tineretii
despre
Antioxidant Antioxidanti
